hs-CRP — Systemic Inflammation

hs-CRP measures small rises in C-reactive protein, a non-specific inflammation marker. The AHA classes below 1.0 mg/L as low cardiovascular risk.

2 min read June 29, 2026 AgeGen Editorial
hs-CRP — Systemic Inflammation — AgeGen

High-sensitivity C-reactive protein (hs-CRP) measures small rises in CRP, a protein the liver makes when there is inflammation, and higher levels are linked to a higher risk of heart attack, stroke and heart disease. Because infection, injury or chronic disease can all raise it, a raised reading is repeated before it is read as a pattern.

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hs-CRP is the number that tells you whether inflammation is running in the background.

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Mr. Age is AgeGen's editorial character. Facts come from the protocol above.

The biomarker

  • Name: hs-CRP (high-sensitivity C-reactive protein)
  • Units: mg/L
  • Risk categories (AHA, per MedlinePlus): lower than 1.0 low risk; 1.0–3.0 average risk; higher than 3.0 high risk of cardiovascular disease. Ranges vary by lab.
  • Target: below 1.0 mg/L is the AHA low-risk category.

How to read your result

Result (mg/L)AHA category
< 1.0Low risk
1.0–3.0Average risk
> 3.0High risk
Any raised resultA cold or a long run can raise CRP briefly — the test is done twice, about two weeks apart

What to do with the result

  • Repeat. Test twice, about two weeks apart, because a cold or a long run can raise CRP briefly.
  • Timing. Be tested when you are well rather than during an infection.
  • Clinician. Discuss a raised result with your clinician.

Why this test is worth asking for

  • The hs-CRP assay is used to estimate heart-disease risk, with published AHA risk categories.
  • Because CRP is non-specific, a repeat test about two weeks apart separates a brief rise from a steady level.

Sources

AgeGen lab guides are educational only. We do not provide medical diagnosis, prescribe brands, or recommend specific doses. Talk to a licensed clinician before changing your supplement or medication routine.

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