Fasting Insulin and HOMA-IR — 60-Second Protocol
36s · captions burned in · sound on
lab guide · 2026-09-07
Fasting insulin moves years before fasting glucose does.
Fasting insulin and the derived HOMA-IR score reveal insulin resistance years before fasting glucose drifts up. The earliest commonly available marker of metabolic dysfunction.
The protocol
| Units | µU/mL; HOMA-IR unitless |
| Standard range | Insulin < 25; HOMA-IR varies by lab |
| Optimal range | Insulin < 6; HOMA-IR < 1.5 |
| 5-8 | acceptable |
| 8-12 | borderline |
| ≥12 | insulin resistance likely |
| HOMA-IR >2 | insulin resistance |
| HOMA-IR >3 | clear resistance |
| insulin <5 | optimal |
| Diet | reduce refined carbs and sugary drinks |
| Weight | 5–10% loss often normalises |
| Testing | recheck every 3 months |
| Movement | add daily walking + 2x strength |
Full transcript
Fasting insulin moves years before fasting glucose does. Together with the HOMA-IR score it is the earliest commonly available marker of metabolic dysfunction. Under five is optimal, five to eight acceptable, eight to twelve borderline, twelve and above means insulin resistance is likely. On HOMA-IR, above two is resistance and above three is clear resistance. Fewer refined carbs and sugary drinks, daily walking and two strength sessions a week; a five to ten percent weight loss often normalises it. Recheck every three months, with a clinician reading it. agegen.ai. Generate your prime age! ~~ Mr. Age
Sources
- https://medlineplus.gov/lab-tests/insulin-in-blood/
- https://www.niddk.nih.gov/health-information/diabetes/overview/what-is-diabetes/prediabetes-insulin-resistance
Find out which protocol you actually need
Your passport age is a date. Your Prime Age is the age your habits suggest — 12 questions, 2 minutes, no signup.
Take the 2-minute quiz A new protocol daily on TelegramEducational content, not medical advice. Talk to a licensed clinician before changing how you treat a health condition.