Estradiol — Female Cycle + Perimenopause Marker
Estradiol is the primary oestrogen of the reproductive years. Levels vary across the cycle; perimenopause shows wide swings. Interpret with cycle day or status.
Estradiol is the primary oestrogen of the reproductive years and a key marker of the female menstrual cycle and perimenopause. Levels vary across the menstrual cycle, and perimenopause shows wide swings before the post-menopausal floor — always interpret with cycle day or menopausal status.
The biomarker
- Name: Estradiol (Women)
- Units: pg/mL
- Standard reference range: Follicular 12.5–166; mid-cycle 85.8–498; luteal 43.8–211; post-menopause < 6
- Optimal range: cycle-day-dependent
How to read your result
| Value | Interpretation |
|---|---|
| Cycle pattern normal | Healthy cycle |
| Low (pre-menopause) | Investigate amenorrhea, low body fat, over-training |
| Perimenopause | Swings expected — interpret with symptoms |
| Post-menopause | < 6 pg/mL typical |
What moves the needle
- Diet. Adequate dietary fat, calories.
- Track. Cycle day + symptoms.
- Movement. Strength training preserves bone.
- Clinician. OB/GYN referral for symptom-led concerns.
Why this test is worth asking for
- Estradiol is the primary oestrogen of the reproductive years, so its pattern reflects cycle health directly.
- Perimenopause shows wide swings before the post-menopausal floor — a single reading only makes sense alongside cycle day or menopausal status.
- Read with symptoms, it helps distinguish a normal cycle from amenorrhea, low body fat, or over-training.
Related protocols
- Zinc — Immune + Hormone Cofactor
- TSH, Free T3 and T4 — Thyroid Panel
- Testosterone, Total and Free (Men)
Sources
AgeGen lab guides are educational only. We do not provide medical diagnosis, prescribe brands, or recommend specific doses. Talk to a licensed clinician before changing your supplement or medication routine.
