Homocysteine — B-Vitamin + Vascular Marker
Homocysteine is broken down using vitamin B12, B6 and folate. A high level may mean that process is not working or B vitamins are lacking, and is linked to heart disease risk.
Homocysteine is an amino acid your body breaks down using vitamin B12, vitamin B6 and folate — a high level may mean that process is not working properly or that you are short of those B vitamins, and it is linked to a higher risk of heart disease and stroke.
The biomarker
- Name: Homocysteine
- Units: µmol/L
- Standard reference range: about 5–15 µmol/L in a healthy person; 15–30 mild; 30–100 moderate; > 100 severe (ranges vary by lab)
How to read your result
| Value (µmol/L) | Interpretation |
|---|---|
| 5–15 | Typical range in a healthy person |
| 15–30 | Mild elevation — ask your clinician about B12, folate and B6 status |
| 30–100 | Moderate elevation — see a clinician |
| > 100 | Severe — see a clinician |
What moves the needle
- Clinician. Ask whether vitamin B12, folate and B6 status should be checked alongside it.
- Caution. Do not start B-vitamin supplements to move this number without a clinician.
Why this test is worth asking for
- Your body uses vitamin B12, vitamin B6 and folate to break homocysteine down, so a high value points to that process — the conversation is about B-vitamin status, not the number alone.
- Homocysteine that is not broken down can build up and damage arteries, which may raise the risk of heart attack, stroke and blood clots.
- Pairs naturally with the Folate (RBC) and Vitamin B12 + MMA guides already in this library.
Homocysteine is one of the markers the at-home methylation kit reports.
At-Home DNA + Methylation Test
An at-home kit combining a genetic (DNA) panel with a methylation blood test (homocysteine, folate, B12) — the methylation markers tie into the epigenetic-clock research on biological aging.
See it in the shop →Illustrative photo. We may earn a commission — the affiliate link and the full disclosure live on our shop page.
Related protocols
- Omega-3 Index — EPA + DHA Blood Test
- Lp(a) — Genetic Cardiovascular Risk
- Lipid Panel — LDL, HDL, Triglycerides
Sources
AgeGen lab guides are educational only. We do not provide medical diagnosis, prescribe brands, or recommend specific doses. Talk to a licensed clinician before changing your supplement or medication routine.
