Your daily AI-assisted longevity operating system.

A 50 g handful of walnuts, almonds, and 85% dark chocolate — 280 kcal and ~200 mg of flavonoids. Polyphenols, magnesium, and omega-3 ALA in under a minute.

A ginger-soy salmon bowl with 42 g of protein and 520 kcal — leading the rotation for marine omega-3 (~2.2 g EPA+DHA) and isoflavones in a single dinner.

This week’s digest covers daily longevity protocols, curated menus, and major news from a $435M NewLimit raise to a Phase 1 drug clearing toxic cholesterol.

RBC folate reflects long-term folate status better than serum folate. Required for methylation, DNA synthesis, and homocysteine clearance.

Fibrinogen is a clotting factor and acute-phase reactant. Chronically elevated values track with cardiovascular and stroke risk. Use alongside hs-CRP.

Ferritin reflects the body iron storage. Low ferritin precedes anaemia and shows up first as fatigue, brittle hair, restless legs, or breathlessness on exertion.

Plasma glucose measured after an 8–12 hour fast. The simplest standalone metabolic marker, available on every basic panel.

Fasting insulin and the derived HOMA-IR score reveal insulin resistance years before fasting glucose drifts up — the earliest commonly available metabolic marker.

Serum creatinine and the calculated eGFR estimate the kidney filtration rate. Heavily muscled adults run higher creatinine without true kidney impairment.

Estradiol is the primary oestrogen of the reproductive years. Levels vary across the cycle; perimenopause shows wide swings. Interpret with cycle day or status.

DHEA-S is the most abundant circulating steroid hormone. It declines after age 30; low values for age track with stress load, under-recovery, and aging.

Alanine and aspartate transaminases leak into blood when liver cells are stressed. Mild persistent elevations are the most common signal of fatty liver disease.