TSH, Free T3 and T4 — Thyroid Panel — 60-Second Protocol
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lab guide · 2026-09-08
TSH can look normal while the active hormone is not.
TSH is made by the pituitary gland and tells the thyroid how much hormone to make; Free T4 and T3 measure thyroid hormone in the blood. Read together, they help show whether a problem starts in the thyroid gland or in the pituitary.
The protocol
| Units | TSH mIU/L; Free T3 and Free T4 per lab (commonly pmol/L) |
| Standard range | TSH 0.4–4.5 mIU/L for a non-pregnant adult; Free T3 and Free T4 per the lab's own range (ranges vary by lab) |
| high TSH + low free T4 | may mean the thyroid is making too little hormone — see clinician |
| low TSH + high free T4 | may mean the thyroid is making too much hormone — see clinician |
| normal or high TSH + high free T4 | may mean a pituitary condition — see clinician |
| Testing | if TSH is abnormal, your clinician will probably order T4, T3 and thyroid antibody tests |
| Clinician | endocrinology referral if hypo/hyper confirmed |
Full transcript
TSH can look normal while the active hormone is not. TSH measures the signal from the pituitary; free T3 and free T4 measure the active and storage hormones. Together the panel separates a thyroid problem from a pituitary or conversion one. Optimal is TSH one to two, free T3 five to six and a half, free T4 fifteen to twenty-two. Above four points to hypothyroidism and below nought point four to hyperthyroidism — both go to a clinician. Between two and a half and four is subclinical: watch it alongside symptoms. agegen.ai. Generate your prime age! ~~ Mr. Age
Sources
- https://medlineplus.gov/lab-tests/tsh-thyroid-stimulating-hormone-test/
- https://medlineplus.gov/thyroidtests.html
- https://my.clevelandclinic.org/health/diseases/23903-subclinical-hyperthyroidism
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