Morning Cortisol — Stress Axis Marker — 60-Second Protocol

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lab guide · 2026-10-03

Cortisol changes through the day, so the result only means something against the time it was drawn.

Cortisol, made by the adrenal glands, helps the body respond to stress and regulate blood sugar and metabolism. Levels vary through the day, so the test is usually done early in the morning and read against a time-specific range.

The protocol

Unitsµg/dL
Standard range5–25 (8 a.m. sample; ranges vary by lab)
above the rangehas several possible causes; the most common cause of abnormal cortisol is long-term steroid medicine use or stopping it suddenly; stress and exercise can also raise cortisol
below the rangehas several possible causes; more tests are needed to find which
any out-of-range resultdoes not always mean a condition that needs treatment; a cortisol test alone cannot diagnose the cause
Clinicianan abnormal result is usually followed by more tests; review it with a clinician
Medicinestell your provider about every medicine you use, including skin creams
Preparationrest before the test — stress and exercise can raise cortisol; follow the draw time your provider gives

Full transcript

Cortisol changes through the day, so the result only means something against the time it was drawn. An eight a.m. sample reads against about five to twenty-five micrograms per decilitre, and ranges vary by lab. Stress and exercise raise it, so rest before the draw. Out of range does not always mean a condition — review it with a clinician. agegen.ai. Generate your prime age! ~~ Mr. Age

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Educational content, not medical advice. Talk to a licensed clinician before changing how you treat a health condition.